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Philippe Major Selected Research

Rhabdomyoma

2/2017Accelerated Cardiac Rhabdomyoma Regression with Everolimus in Infants with Tuberous Sclerosis Complex.
4/2015Use of mTOR inhibitor everolimus in three neonates for treatment of tumors associated with tuberous sclerosis complex.
11/2014Oral everolimus treatment in a preterm infant with multifocal inoperable cardiac rhabdomyoma associated with tuberous sclerosis complex and a structural heart defect.

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Philippe Major Research Topics

Disease

19Tuberous Sclerosis (Bourneville's Disease)
01/2021 - 07/2008
10Epilepsy (Aura)
01/2019 - 07/2008
7Drug Resistant Epilepsy
01/2022 - 08/2008
3Rhabdomyoma
02/2017 - 11/2014
3Neoplasms (Cancer)
02/2017 - 03/2011
3Astrocytoma (Pilocytic Astrocytoma)
04/2015 - 10/2010
3Infantile Spasms (West Syndrome)
07/2010 - 07/2008
2Seizures (Absence Seizure)
04/2017 - 02/2009
2Partial Epilepsies (Epilepsy, Partial)
12/2015 - 07/2008
2Intellectual Disability (Idiocy)
08/2014 - 11/2013
2Hamartoma
11/2013 - 10/2010
2Cysts
12/2009 - 03/2009
1Down Syndrome (Down's Syndrome)
01/2021
1Pancreatitis
01/2020
1Drug-Related Side Effects and Adverse Reactions
01/2020
1Brain Diseases (Brain Disorder)
01/2019
1Brain Hypoxia-Ischemia (Hypoxia Ischemia, Brain)
04/2017
1Congenital Heart Defects (Congenital Heart Defect)
02/2017
1Port-Wine Stain (Nevus Flammeus)
11/2016
1Hemangioma (Angioma)
11/2016
1Sturge-Weber Syndrome (Sturge-Kalischer-Weber Syndrome)
11/2016
1Paraganglioma (Paragangliomas)
07/2016
1Renal Cell Carcinoma (Grawitz Tumor)
07/2016
1von Hippel-Lindau Disease (von Hippel Lindau Disease)
07/2016
1Kidney Neoplasms (Kidney Cancer)
07/2016
1Pheochromocytoma
07/2016
1Leiomyomatosis
07/2016
1Birt-Hogg-Dube Syndrome
07/2016
1Lymphangioleiomyomatosis (Lymphangiomyomatosis)
08/2015
1Respiratory Insufficiency (Respiratory Failure)
08/2015
1Angiomyolipoma
04/2015
1Pulmonary Atresia (Pulmonary Valve Atresia)
11/2014
1Ventricular Heart Septal Defects (Ventricular Septal Defect)
11/2014
1Autistic Disorder (Autism)
11/2013
1Megalencephaly
11/2013
1Brain Neoplasms (Brain Tumor)
03/2011
1Inborn Genetic Diseases (Disease, Hereditary)
07/2010
1Lennox Gastaut Syndrome
07/2010
1Cognitive Dysfunction
07/2010

Drug/Important Bio-Agent (IBA)

16trans-sodium crocetinate (crocetin)IBA
01/2021 - 07/2008
4Anticonvulsants (Antiepileptic Drugs)IBA
04/2017 - 02/2009
3EverolimusFDA Link
02/2017 - 11/2014
2CannabidiolIBA
01/2022 - 01/2019
2TOR Serine-Threonine KinasesIBA
02/2017 - 04/2015
2VigabatrinFDA Link
01/2016 - 07/2008
2MTOR InhibitorsIBA
04/2015 - 03/2011
2Proteins (Proteins, Gene)FDA Link
11/2013 - 03/2011
1Dronabinol (THC)FDA LinkGeneric
01/2022
1Valproic Acid (Depakote)FDA LinkGeneric
01/2020
1Retinaldehyde (Retinal)IBA
11/2016
1LacosamideFDA Link
12/2015
1lipoarabinomannan (LAM)IBA
08/2015
1Fragile X Mental Retardation ProteinIBA
08/2014
1Mechanistic Target of Rapamycin Complex 1IBA
11/2013
1Sirolimus (Rapamycin)FDA Link
10/2010
1Levetiracetam (Keppra)FDA LinkGeneric
10/2008

Therapy/Procedure

3Therapeutics
02/2017 - 08/2008
1Rewarming
04/2017
1Electrodes (Electrode)
03/2011
1Ambulatory Care (Outpatient Care)
07/2010
1Vagus Nerve Stimulation
08/2008